Abstract
Objective: The objective of this study was to report initial experience using aspiration thrombectomy with the Indigo Aspiration System, as the first line treatment for acute iliofemoral deep vein thrombosis (DVT).
Methods: This study is a retrospective case review of patients with acute symptomatic iliofemoral DVT who underwent aspiration thrombectomy using the Indigo Aspiration System between December 2015 and January 2018 at three centres. Data on patient demographics, adjunctive treatments, and intraprocedural complications were collected from electronic patient records. Technical success was defined as antegrade flow and maximal luminal stenosis of 30% assessed following the use of Indigo System. Clinical and imaging follow-up was conducted at 30 days and 12-months.
Results: A total of 35 patients (20 females; median age 43 years) met study criteria. Technical success was achieved in 80% (28/35) of patients, with the Indigo System alone. There were no intra-procedure or immediate post-procedure complications. Adjunctive interventions included venous stents (with post-dilatation) in 97.1% of patients, thrombolytics in 37.1% of patients, and caval filters in 14.2% of patients. No DVT recurrence, pulmonary embolism, or deaths occurred over 12 months of follow-up except for one patient with active neo-plastic disease. Moderate to severe post-thrombotic syndrome occurred in two patients.
Conclusion: This study provides evidence that aspiration thrombectomy using the Indigo System is an effective treatment for acute iliofemoral DVT. There were no procedural complications and complication rates over the 12-month follow-up period were low.
Keywords
Iliofemoral, Deep Vein Thrombosis, Thrombectomy, Aspiration Thrombectomy